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George W Sledge Selected Research

N- hydroxy- 2- (((4'- methoxyphenyl)sulfonyl)benzylamino)- 3- methylbutanamide

1/2004Comparative studies of potential cancer biomarkers carbon-11 labeled MMP inhibitors (S)-2-(4'-[11C]methoxybiphenyl-4-sulfonylamino)-3-methylbutyric acid and N-hydroxy-(R)-2-[[(4'-[11C]methoxyphenyl)sulfonyl]benzylamino]-3-methylbutanamide.

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George W Sledge Research Topics

Disease

137Breast Neoplasms (Breast Cancer)
07/2022 - 06/2002
98Neoplasms (Cancer)
07/2022 - 11/2002
17Neoplasm Metastasis (Metastasis)
01/2018 - 01/2003
10Triple Negative Breast Neoplasms
01/2022 - 12/2008
9Disease Progression
01/2022 - 12/2003
5Diarrhea
09/2021 - 06/2008
4Ovarian Neoplasms (Ovarian Cancer)
01/2021 - 01/2007
4Circulating Neoplastic Cells
10/2019 - 09/2014
4Hypertension (High Blood Pressure)
01/2018 - 10/2008
3Fatigue
02/2022 - 09/2017
3Nausea
01/2020 - 06/2008
3Peripheral Nervous System Diseases (PNS Diseases)
01/2017 - 11/2015
3Heart Failure
01/2017 - 12/2015
2Neutropenia
09/2021 - 09/2017
2Hemorrhage
01/2021 - 01/2018
2Melanoma (Melanoma, Malignant)
01/2020 - 07/2015
2Cardiotoxicity
01/2018 - 12/2015
2Osteoporosis
07/2017 - 04/2013
2Metabolic Bone Diseases (Osteopenia)
07/2017 - 04/2013
2Obesity
07/2015 - 12/2012
2Hypoxia (Hypoxemia)
08/2009 - 09/2008
2Exanthema (Rash)
06/2008 - 03/2004
2Glioma (Gliomas)
10/2007 - 06/2006
2Pathologic Processes
10/2005 - 10/2003
1COVID-19
07/2022

Drug/Important Bio-Agent (IBA)

39Hormones (Hormone)IBA
02/2022 - 10/2006
21Paclitaxel (Taxol)FDA LinkGeneric
01/2021 - 02/2003
20Doxorubicin (Adriamycin)FDA LinkGeneric
12/2018 - 02/2003
18ErbB Receptors (EGF Receptor)IBA
09/2021 - 08/2006
17Estrogen ReceptorsIBA
01/2022 - 03/2006
17Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
01/2015 - 06/2002
15Bevacizumab (Avastin)FDA Link
02/2022 - 10/2003
15Trastuzumab (Herceptin)FDA Link
09/2017 - 04/2003
12Proteins (Proteins, Gene)FDA Link
01/2021 - 01/2003
12AnthracyclinesIBA
01/2020 - 04/2003
12Cyclophosphamide (Cytoxan)FDA LinkGeneric
12/2018 - 03/2004
11abemaciclibIBA
01/2022 - 09/2017
11Biomarkers (Surrogate Marker)IBA
12/2018 - 03/2004
10Fulvestrant (Faslodex)FDA Link
01/2022 - 06/2012
10taxaneIBA
01/2020 - 12/2009
9Biological ProductsIBA
12/2019 - 06/2002
8RNA (Ribonucleic Acid)IBA
10/2016 - 06/2007
7Pharmaceutical PreparationsIBA
07/2022 - 12/2006
7Anastrozole (Arimidex)FDA LinkGeneric
04/2021 - 06/2012
7Docetaxel (Taxotere)FDA Link
07/2015 - 01/2005
6DNA (Deoxyribonucleic Acid)IBA
01/2021 - 04/2006
6human ERBB2 proteinIBA
07/2018 - 12/2009
6Carbon-11IBA
10/2008 - 11/2006
5exemestane (Aromasin)FDA Link
01/2018 - 04/2013
5Phosphotransferases (Kinase)IBA
01/2016 - 01/2006
5ParaffinIBA
11/2015 - 04/2006
5EnzymesIBA
04/2013 - 11/2004
5Matrix Metalloproteinase InhibitorsIBA
03/2004 - 10/2002
4Progesterone Receptors (Progesterone Receptor)IBA
01/2018 - 04/2011
4Aromatase InhibitorsIBA
01/2018 - 04/2013
4Capecitabine (Xeloda)FDA Link
05/2014 - 11/2004
4TamoxifenFDA LinkGeneric
05/2013 - 03/2004
4Matrix Metalloproteinases (MMPs)IBA
10/2003 - 10/2002
3Estrogens (Estrogen)FDA Link
11/2018 - 06/2012
3Fluorouracil (Carac)FDA LinkGeneric
08/2017 - 11/2004
3Messenger RNA (mRNA)IBA
10/2016 - 11/2010
3Monoclonal AntibodiesIBA
12/2015 - 10/2006
3Small Interfering RNA (siRNA)IBA
10/2014 - 03/2006
3Tyrosine Kinase InhibitorsIBA
06/2012 - 10/2006
3Gefitinib (Iressa)FDA Link
06/2012 - 08/2006
3Aromatase (CYP19)IBA
12/2010 - 01/2007
3Vascular Endothelial Growth Factor Receptors (VEGF Receptors)IBA
08/2009 - 01/2006
32-MethoxyestradiolIBA
02/2007 - 10/2005
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
12/2006 - 10/2005
2Letrozole (Femara)FDA LinkGeneric
04/2021 - 04/2013
2Circulating Tumor DNAIBA
01/2016 - 09/2014
2RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA
11/2015 - 11/2011
2Imatinib Mesylate (Gleevec)FDA Link
07/2015 - 12/2007
2Formaldehyde (Formol)FDA Link
11/2013 - 03/2008
2Steryl-Sulfatase (Steroid Sulfatase)IBA
07/2012 - 11/2009
2Estradiol (Delestrogen)FDA LinkGeneric
07/2012 - 01/2007
2SteroidsIBA
07/2012 - 01/2012
2sulfamic acid (ammonium sulfamate)IBA
07/2012 - 11/2009
2Protein Kinase CIBA
11/2010 - 06/2006
2Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA
10/2010 - 07/2010
2NF-kappa B (NF-kB)IBA
07/2010 - 10/2006
2TubulinIBA
02/2010 - 10/2005
2enzastaurinIBA
12/2009 - 06/2006
2Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA
08/2009 - 09/2008
2Neuropilin-1IBA
08/2009 - 09/2008
2Vascular Endothelial Growth Factor Receptor-2 (Vascular Endothelial Growth Factor Receptor 2)IBA
10/2008 - 09/2008
21,2,3,4-tetrahydroisoquinolineIBA
10/2008 - 10/2007
2Taxoids (Taxanes)IBA
09/2008 - 04/2008
2diphenyl (biphenyl)IBA
10/2007 - 01/2003
2Antineoplastic Agents (Antineoplastics)IBA
12/2006 - 11/2004
2Fluorine-18IBA
11/2006 - 11/2004
2Sunitinib (Sutent)FDA Link
10/2006 - 10/2005
2GemcitabineFDA Link
12/2003 - 04/2003
1CytokinesIBA
02/2022

Therapy/Procedure

79Therapeutics
07/2022 - 01/2003
38Drug Therapy (Chemotherapy)
02/2022 - 02/2003
13Adjuvant Chemotherapy
02/2022 - 12/2006
3Radiotherapy
01/2022 - 07/2012
3Aftercare (After-Treatment)
09/2017 - 12/2006
1Ambulatory Care (Outpatient Care)
07/2022